|
Home >
Technical Articles >
Aloe Vera
NMR
|
Aloe VeraAloe Vera is a common ingredient used in medicinal products, cosmetics, and foods. The primary constituents appear to be polysaccharides, in particular partially acetylated poly-β-1,4-mannans, aka "acemannan" or "aloverose", which are somewhat unique forms of plant mannans. In addition, the material contains smaller amounts of glucose and malic acid. Lactic and acetic acids may also be present due to bacterial, hydrolytic, or thermal degradation. A number of other compounds may also be present in commercial products as preservatives, additives, and impurities. The International Aloe Science Council (IASC) and some countries have developed standards for Aloe Vera products. Aloe products are certified by IASC if they are found to contain the unique acetylated polymannose, contain less than 10 ppm aloin, and pass a facility audit, among other requirements. |
Nuclear Magnetic ResonanceA quantitative analysis of Aloe Vera products using 1H NMR has been reported in the literature by Jiao, et al. The Aloverose is estimated assuming 30% acetylation of the polysaccharide. All components are quantified using nicotinamide as an internal standard. Exova has applied this method to a number of Aloe products. The following components can be quantified in Aloe products by 1H NMR:
Exova operates a 500 MHz Bruker Avance III NMR system compliant with FDA GMP regulations. |
||||||||||||||||||||||||||||||||||
Quantitative 1H NMR of Aloe Vera
